Effect of Different Nuts Oil Consumption on Morphological Features and Some Biomarkers of Inflammation in Adjuvant-Induced Arthritis (AIA) Rat Model

This study evaluated the protective effect of different dietary ω-6/ω-3 ratios in oils obtained from various nuts (walnut, peanut, cashew, and hazelnut) against morphological features markers inflammation on an adjuvant-induced arthritis rat model. Rheumatoid (RA) was induced via intradermal injection heat-killed Mycobacterium tuberculosis. Five groups rats with RA (n = 5) were randomly categorized as follows: control positive, walnut oil group, peanut cashew nut hazelnut group. Another five healthy served a normal non-arthritic (control) We assessed therapeutic effects by measuring scores during experiment serum inflammatory at end study. The levels rheumatoid factor, TNF-α, IL-6, IL-1β, PGE2, significantly (p ≤ 0.05) reduced all treatment groups. daily consumption ameliorates clinical abnormalities inhibiting cells that produce interleukins eicosanoids.